What You Need to Know Before Considering Weight-Loss Medications

2024-06-27

ShedRx

Semaglutide and Tirzepatide are two weight-loss medications that have gained attention for their efficacy in aiding weight loss. Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) that was initially developed for managing type 2 diabetes but has since been approved for weight loss. Tirzepatide, on the other hand, is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist that also supports weight loss.

Ever since Semaglutide and Tirzepatide were introduced as weight-loss drugs, their popularity has skyrocketed. You may have seen all those news stories touting these drugs as the cure for obesity and weight-related complications or perhaps you’ve been awed by the sight of your favorite celebrities shedding pounds and becoming lean and chiseled due to the influence of these medications. Weight-loss medications like Semaglutide and Tirzepatide can certainly help you lose considerable weight, but there are various factors to consider before undergoing treatment.

How Weight-Loss Medications Work

Weight-loss medications such as Semaglutide and Tirzepatide exert their effects through various mechanisms. Semaglutide, a GLP-1 receptor agonist, regulates appetite and food intake by mimicking the action of GLP-1 in the brain. This leads to reduced hunger and increased feelings of fullness, ultimately promoting weight loss. Tirzepatide, a dual GIP and GLP-1 receptor agonist, targets multiple pathways involved in appetite regulation and glucose metabolism. By modulating these pathways, Tirzepatide helps individuals achieve significant weight loss.

How Semaglutide Works for Weight Loss

Semaglutide operates by engaging with glucagon-like peptide-1 (GLP-1) receptors in the brain, imitating the actions of natural GLP-1. GLP-1 is a hormone that plays a crucial role in regulating appetite and food intake. When Semaglutide activates GLP-1 receptors, it triggers signaling pathways that reduce hunger and increase satiety, leading to decreased food consumption.

Additionally, Semaglutide influences gastric motility by delaying gastric emptying. This means that food stays in the stomach longer, prolonging the feeling of fullness and reducing the frequency of hunger pangs. By modulating gastric emptying, Semaglutide contributes to a sense of satiety, making it easier for individuals to control their portion sizes and make healthier food choices.

How Tirzepatide Works for Weight Loss

Tirzepatide, a novel weight-loss medication, operates through a unique dual mechanism of action targeting both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. By activating these receptors, Tirzepatide modulates multiple pathways involved in appetite regulation and glucose metabolism. 

Firstly, Tirzepatide stimulates the GLP-1 receptor, leading to decreased appetite and increased feelings of fullness. This is similar to Semaglutide, but Tirzepatide offers the added benefit of simultaneously activating the GIP receptor. GIP plays a role in regulating energy metabolism and promoting insulin secretion, contributing to improved glycemic control. By targeting both GLP-1 and GIP receptors, Tirzepatide offers a comprehensive approach to weight management, addressing both appetite control and metabolic regulation.

Comparing Semaglutide and Tirzepatide

Both Semaglutide and Tirzepatide are incredibly powerful weight-loss medications that can curb appetite, delay gastric emptying, and help you stick to a low-calorie diet. However, their potential results are slightly different, because Tirzepatide also works on the GIP receptors. Below, we discuss the effectiveness of Semaglutide and Tirzepatide in weight management.

Weight-loss medication can be a great tool to help you reach your weight-loss goals, along with healthy lifestyle habits.

Semaglutide Effectiveness in Weight Management

Semaglutide has been available on the market longer than Tirzepatide and has undergone more extensive clinical studies. Studies have shown that Semaglutide can lead to significant weight loss, with participants experiencing an average weight reduction ranging from 10% to 15% of their initial body weight. This substantial weight loss makes Semaglutide a compelling option for individuals struggling with obesity and related health conditions.

Tirzepatide Effectiveness in Weight Management

Tirzepatide, with its dual action on both the GLP-1 and GIP receptors, holds promise as a potentially more effective weight-loss medication. Clinical trials have demonstrated that Tirzepatide can lead to even greater weight loss compared to Semaglutide, with participants experiencing weight reductions of up to 20% of their initial body weight. This enhanced efficacy may make Tirzepatide an attractive option for individuals who have not achieved significant weight loss with other medications or lifestyle modifications.

Side Effects of Weight-Loss Medications

Like any medication, weight-loss drugs can cause side effects. Common side effects of Semaglutide and Tirzepatide include nausea, vomiting, diarrhea, and constipation. These symptoms typically diminish over time as the body adjusts to these medications. Most providers start patients off with low doses of these medications to give the body the time to adjust before gradually increasing the dose. It’s essential to report any adverse reactions to your provider.

Tips to Manage Side Effects of Weight-Loss Medications:

  • Drink plenty of water throughout the day to help alleviate symptoms like nausea.
  • Eat small, frequent meals to help mitigate gastrointestinal discomfort.
  • Include high-fiber foods such as fruits, vegetables, and whole grains in your diet.
  • Monitor blood sugar levels, as weight-loss medications can affect glucose metabolism.
  • Start with low-intensity exercises and gradually increase intensity to minimize fatigue.
  • Report any adverse reactions or concerns to your healthcare provider promptly.
  • Take medications with meals or at specific times of the day to reduce side effecs.
  • Pay attention to hunger and fullness cues and avoid overeating or rapid consumption of food.

Who Should Consider Semaglutide and Tirzepatide

Semaglutide and Tirzepatide are typically recommended for individuals with a body mass index (BMI) of 30 or higher or a BMI of 27 or higher with comorbidities such as type 2 diabetes. However, Semaglutide and Tirzepatide are extremely versatile medications which can also be used by individuals who have struggled to lose weight through traditional lifestyle changes alone. Furthermore, these medications can also be used by individuals who want to maintain a healthy weight and avoid overeating and weight gain.

You May Be a Candidate for Semaglutide and Tirzepatide If:

  • Your body mass index (BMI) is 30 or higher
  • Your BMI is 27 or higher and you have comorbidities such as type 2 diabetes
  • You have struggled to achieve significant weight loss with lifestyle modifications alone
  • You are committed to making lifestyle changes to support weight-loss efforts
  • Your provider determines that the benefits outweigh the risks for your individual case
  • You are at risk of weight gain due to hormonal imbalances or lifestyle changes
  • You have a history of yo-yo dieting and are seeking a long-term solution for weight management
  • You are motivated to take proactive steps to prevent future weight gain

You May NOT Be a Candidate for Semaglutide and Tirzepatide If:

  • You have a history of pancreatitis or severe gastrointestinal disorders
  • You are pregnant or planning to become pregnant
  • You have a history of thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • You have a known allergy or hypersensitivity to Semaglutide or Tirzepatide
  • You have a history of severe renal impairment or end-stage renal disease
  • You are currently using other weight-loss medications or undergoing treatments for obesity
  • You have a history of eating disorders such as anorexia nervosa or bulimia nervosa
  • You are unable or unwilling to comply with the necessary lifestyle changes
While weight-loss medication can help you lose a great deal of weight, it’s also important to eat a nutritious diet, stay hydrated, and be active.

Lifestyle Changes with Weight-Loss Drugs

While weight-loss medications can help shed pounds, they should be complemented by healthy lifestyle changes. That’s because Semaglutide and Tirzepatide don’t cause weight loss directly. Instead, they allow you to stick to low-calorie diets more comfortably and address the factors that usually lead to weight regain, such as hunger pangs and cravings. The only way to lose weight is by maintaining a calorie deficit, which can be done through physical activities and a balanced diet. As such, weight-loss medications must be a part of a comprehensive weight-loss plan.

Lifestyle Changes to Boost Weight-Loss Results:

  • Incorporate at least 30 minutes of moderate-intensity exercise most days of the week.
  • Consume nutrient-dense foods, including fruits, vegetables, lean proteins, and whole grains.
  • Use smaller plates and measure serving sizes to manage portion sizes.
  • Minimize consumption of processed and high-calorie foods, such as sugary snacks.
  • Drink plenty of water to stay hydrated and prevent mistaking thirst for hunger.
  • Aim for 7-9 hours of quality sleep per night to support weight loss and overall health.
  • Practice stress-reduction techniques like meditation and deep breathing exercises.
  • Keep a food diary, monitor physical activity, and track weight-loss progress.
  • Join a weight-loss group and enlist the help of a friend or family member to stay motivated.

Patient Experiences with Weight-Loss Medications

Listening to the experiences of others who have tried Semaglutide or Tirzepatide can provide valuable insights. Sharing experiences and support within a community or with healthcare professionals can be beneficial.

Testimonials from Real Patients:

  • “ShedRx was easy and pocket-friendly. I got my compounded medication almost immediately after my appointment. I took my first shot Monday, and as of Friday, I’m 6lbs down! I have normal energy, no shakes or jitters, and feel perfectly fine, just not hungry. This is awesome!” — Trina
  • “I highly recommend ShedRx. The customer service has been amazing. I have been taking Semaglutide for five weeks and have already lost 13 pounds. I am excited to continue the journey!” — Shanna
  • “I’ve been using the medication for almost three weeks and have lost 9 pounds!” — Linda

Weight-loss medications such as Semaglutide and Tirzepatide can be valuable tools in managing obesity and excess weight. It’s important to understand their mechanisms of action, potential risks and benefits, and the importance of lifestyle modifications. By working closely with healthcare providers and making informed decisions, you can achieve successful and sustainable weight loss with these medications. If you’re prepared to initiate your weight-loss journey, submit your application to get started!

Semaglutide helps to curb appetite and gain control over cravings to aid weight loss.

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Meet Shed Protein’s lighter, fruitier protein option. This new supplement offers a refreshing alternative to our chocolate Shed Protein. It’s a two-in-one powder which provides low-calorie protein to support muscle and electrolytes to boost energy, all while hydrating in a flavorful way.

What’s is Shed Clear Protein Made Up Of?

  • Clear Whey Protein Isolate: This is an extremely purified version of whey protein and helps with maintaining muscle, as well as repairing and growing it.
  • Sodium: By managing water, sodium balances fluid and hydration.
  • Potassium: Potassium encourages balance of electrolytes and well-functioning muscles in order to evade muscle fatigue, dehydration, and bloating.
  • Magnesium: This assists in producing energy and relaxing muscles to help with metabolism, muscle fuel, and to avoid cramps.

Why is Shed Clear Protein Important?

As shown, Shed Clear Protein is made up of these specific ingredients to support you in specific ways. These include:

  • Electrolyte balance and hydration
  • Build and maintain muscle
  • Aid metabolism, satiety, and weight loss
  • Energy support
Clear Protein is the answer to a refreshing, energizing protein supplement, now live through ShedRx.
Clear Protein is the answer to a refreshing, energizing protein supplement, now live through ShedRx.

Why Does Shed Clear Protein Support a GLP-1 Medication Journey?

Easily-Digestible Formula:

Clear Whey protein isolate, a highly bioavailable form of protein, is easier to digest and, with the benefit of added electrolytes, helps hydrate on a cellular level, optimizing the breakdown of nutrients more effectively.

Promotes Protein Intake and Hydration for Satiety and Recovery:

Clear Whey protein isolate supports muscle repair and growth. Combined with electrolytes to help restore sodium, potassium, and magnesium balance, this mix is ideal for post-exercise recovery or daily needs, delivering a dual benefit for optimal performance.

Convenient Way to Get Protein and Stay Hydrated:

Convenient grab-and-go packets are designed to support your nutritional needs between meals or as a quick boost during the day. Shed Clear Protein encourages water intake with three refreshing flavors, making hydration enjoyable, nourishing, and satisfying.

How to Use Shed Clear Protein

Add 1 packet to a bottle, shaker cup, or glass and shake or stir well to mix. Wait to let the foam settle and enjoy anytime. Shed Clear Protein provides a lighter protein option when appetite is low. It’s a great snack between meals to boost protein intake and sustain energy levels. It also provides a way to hydrate during or after a workout for muscle repair and electrolyte replacement.

Try It Out

See for yourself how Shed Clear Protein can impact how you feel in your health and wellness journey. Head here to grab yours now!

The start of a new year is the perfect time to set fresh health and wellness goals. For many, this includes tackling weight loss, which can often feel overwhelming without the right tools and support. At ShedRx, we understand that the journey to better health is unique for everyone, which is why we’ve developed a range of premium supplements designed to make the process easier, more effective, and sustainable.

Whether you’re looking to boost energy, curb cravings, or support your metabolism, our products are here to help you stay motivated and on track every step of the way. To get a snapshot of Shed Supplements, read over this info to learn how they can be a powerful ally in helping you achieve your weight-loss goals this upcoming year and beyond.

GLP-1 Revive

What It Is: With GLP-1 Revive, you’ll get targeted relief for nausea, digestion, and reflux along with metabolism and energy support, allowing you to stay focused and comfortable while on a GLP-1

What’s In It:

  • Vitamins and minerals—Active forms of Vitamin B12, folate, and CoQ10 support energy levels, while chromium picolinate aids in metabolism and may contribute to fat loss.
  • Digestive enzymes—Papain, bromelain, and protease break down protein, while cellulase helps digest fiber. Together, they support digestion, enhance nutrient absorption, and reduce digestive discomfort.
  • Herbs—Ginger root, chamomille, and lemon balm extract aid in relieving indigestion, bloating, gas, and nausea, common side effects of a GLP-1 medication.
  • Propbiotic—Sporevia is a patented probiotic backed by science that supports overall digestive health. This is done by supporting healthy gut bacteria in the gut microbiome, reducing digestive upset.
  • Adaptogenic
mushrooms—Reishi, Lion’s Mane, and Cordyceps help support stress, metabolic repair, and energy levels. They’re rich in beta-glucans to support gut health.

What It Does:

  • Nausea, reflux, gas, and bloating relief
  • Metabolism, weight-loss, and body composition support
  • Enhanced nutrient absorption and replenishment
  • Energy support and help in combating fatigue
  • Digestion support and overall gut health

GLP-1 Boost

What It Is: Through craving control and reduced appetite, GLP-1 Boost provides an alternative to injections, while still reaching your weight-loss goals.

What’s In It:

  • Vitamin B12—Essential for energy production and a well-functioning metabolism in its bioavailable form
  • Eriomin—A lemon-flavonoid antioxidant which encourages GLP-1 production and supports insulin sensitivity, inflammation, and gut health
  • Berberine—Comes from Berberis aristata plant bark and helps enhance glucose metabolism and GLP-1 levels for better blood sugar control and reduced cravings
  • Capsaicin—The active compound in chili peppers, boosts metabolism, curbs appetite and supports fat burning

What It Does:

  • Metabolism support
  • Craving control
  • Blood glucose support
  • Appetite control
Shed Supplements are a great resource to replenish your body, especially while taking weight-loss medications, when vital nutrients can be lacking.
Shed Supplements are a great resource to replenish your body, especially while taking weight-loss medications, when vital nutrients can be lacking.

Shed Protein

What It Is: This advanced 100% whey protein isolate offers a rich, decadent chocolate flavor, crafted to deliver high-quality protein to support muscle growth and recovery.

What’s In It:

  • 22 g protein—Supports muscle preservation and satiety
  • 2 g fat—Provides essential fatty acids for overall health
  • 2 g—Helps regulate blood sugar levels without excessive calorie
  • 110 calories—Offers a low-calorie option for weight-conscious individuals

What It Does:

  • Muscle preservation
  • Satiety and cravings control
  • Metabolic boost
  • Blood sugar stability

Smoothie Greens

What It Is: GLP-1 medications can make it harder to get enough fiber, leading to constipation and bloating. Smoothie Greens provide fiber to help regulate your digestive system.

What’s In It:

  • Spirulina—Offers antioxidant and anti-inflammatory properties
  • Wheat grass—Boosts immunity and enhances energy levels
  • Ginger pander—aids in digestion and reduces nausea

What It Does:

  • Supports metabolism and digestion
  • Helps digestion
  • Naturally increases energy levels
  • Fills nutritional gaps
Shed Supplements are a great resource to replenish your body, especially while taking weight-loss medications, when vital nutrients can be lacking.
Shed Supplements are a great resource to replenish your body, especially while taking weight-loss medications, when vital nutrients can be lacking.

Shed Collagen Peptides

What It Is: This is essential for maintaining a healthy level of collagen in the body. Collagen is one of the most abundant proteins in the body and is responsible for keeping the skin, hair, and nails healthy.

What’s In It:

  • Glycine
  • Proline
  • Hydroxyproline
  • Alanine

What It Does:

  • Skin health
  • Hair health
  • Nails health

Magnesium Glycinate

What It Is: Magnesium Glycinate benefits the body by reducing cellular stress, which in turn can help support normal blood pressure, sleep, and support overall wellbeing.

What’s In It:

  • Mineral magnesium—helps to be more bioavailable and gentle on the stomach
  • Glycine, an amino acid—helps to be more bioavailable and gentle on the stomach

What It Does:

  • Sleep support
  • Calms nerves
  • Bone health
  • Manages blood pressure
  • Helps with muscle relaxation, cramping, and spasms

No matter where you are at in your wellness journey, it’s always important to make sure you’re getting the proper support your body needs to function at its finest. To check out Shed Supplements and discover how they can benefit you in your health journey, whether on a GLP-1 medication or not, click here.

Another holiday season has come and gone. The air is filled with talk of New Year’s resolutions, fresh goals, and the promise of a new you, all aimed at making this year better than the last. However, what sets this year apart from the others? Perhaps you feel you indulged a bit too much, enjoyed more drinks than intended, or gained a few pounds. We often end up blaming ourselves, feeling ashamed for lacking willpower and resort to depriving ourselves of certain foods, embarking on cleanses, and starting yet another weight-loss journey. If any of this resonates with you, then keep reading!

There’s a different approach to overcoming guilt and self-criticism, allowing you to feel empowered and motivated as we step into the New Year. Research indicates that by mid-February, 80% of New Year’s resolutions have already fallen by the wayside. Don’t worry though, because it’s not all your fault! Many of us set unrealistic goals, lack a solid plan, don’t have enough accountability, or fail to establish a strong internal incentive for change. We often start too aggressively and don’t align our goals with sufficient motivation which leads to self-criticism. Overcoming that self-criticism is like building any other muscle—it requires practice. Cultivating self-compassion, surrounding yourself with support, staying mindful, reframing setbacks, and celebrating small victories are all important factors to stay on track and create lasting change. Let’s explore some tips to kick off this New Year with a fresh approach.

Learn how you can overcome guilt and self-criticism, in order to feel empowered and motivated as you enter into the New Year.
Learn how you can overcome guilt and self-criticism, in order to feel empowered and motivated as you enter into the New Year.

Begin by asking yourself why you want this change:

  • What significance does it hold for you?
  • What might happen if you don’t pursue this change?
  • What experiences could you gain by making this shift?

This reflection gives you a foundation for understanding your motivations. Next, break your goal down into manageable steps. While you may know your ultimate objective, like losing weight, what are the actionable steps to get there? For instance, if your goal is weight loss, whether you’re trying this for the first time, have tried before, or are starting a new medication with ShedRx, consider the foundational elements:

  • Hydration: Begin by focusing on hydration in January. How can you ensure you’re drinking enough water throughout the day?
  • Movement: In February, focus on incorporating more movement into your routine. How can you fit in a few days of
    activity? Could you start counting your steps each day?
  • Nutrition: After adding some movement, our bodies feel better and we need to introduce more nutrient-dense foods. This is where meal planning and prepping can be quite beneficial. By planning your meals, you can avoid the temptation of fast food on your way home from work.

The key is to introduce one new habit each month or, if you are feeling motivated, each week, building a solid foundation for lasting change. Instead of feeling guilty for not meeting lofty expectations, set small, achievable goals that allow you to celebrate your accomplishments. As you continue to achieve these small goals, you’ll find renewed motivation to keep going. You’ll start to notice positive changes, which is incredibly rewarding. Remember,
only you can rewrite your story. Rather than dwelling on past disappointments, let’s embrace the New Year with the affirmation that you can succeed! You are capable of overcoming challenges! Speak to yourself as you would to a friend and remind yourself of the difficult things you’ve already accomplished. This time, you’ll be better prepared. You’ve got this!

Sign up to meet with a ShedRx healthcare provider today and begin working on a healthier you.

Get Started for Only $49

Sign up to meet with a ShedRx healthcare provider today and begin working on a healthier you.